Division 2 Softball : Champions : Schools : Streaks : Series records : Most frequent matchups

 
  Mississippi College 1 - 3 against Alabama-Huntsville

  Games:
    (L)  2023  Mississippi College 1  -  Alabama-Huntsville 5        Tampa FL Regional
    (L)  2023  Mississippi College 3  -  Alabama-Huntsville 5        Tampa FL Regional
    (L)  2021  Mississippi College 4  -  Alabama-Huntsville 10       South Regional
    (W)  2019  Mississippi College 6  -  Alabama-Huntsville 3  (9)   South 2 Regional



 
  Mississippi College 0 - 2 against Auburn-Montgomery

  Games:
    (L)  2024  Mississippi College 1  -  Auburn-Montgomery 14 (5)   South Super Regional
    (L)  2024  Mississippi College 5  -  Auburn-Montgomery 6        South Super Regional



 
  Mississippi College 1 - 0 against Claflin

  Games:
    (W)  2017  Mississippi College 5  -  Claflin 3     South 1 Regional



 
  Mississippi College 0 - 2 against Florida Tech

  Games:
    (L)  2019  Mississippi College 2  -  Florida Tech 5     South 2 Regional
    (L)  2019  Mississippi College 2  -  Florida Tech 5     South 2 Regional



 
  Mississippi College 0 - 1 against Rollins

  Games:
    (L)  2021  Mississippi College 2  -  Rollins 5     South Regional



 
  Mississippi College 1 - 1 against St. Leo

  Games:
    (L)  2025  Mississippi College 0  -  St. Leo 1        South 2 Regional
    (W)  2019  Mississippi College 2  -  St. Leo 1 (10)   South 2 Regional



 
  Mississippi College 2 - 0 against Tampa

  Games:
    (W)  2024  Mississippi College 6  -  Tampa 3     South 2 Regional
    (W)  2024  Mississippi College 3  -  Tampa 0     South 2 Regional



 
  Mississippi College 1 - 0 against Tuskegee

  Games:
    (W)  2023  Mississippi College 8  -  Tuskegee 0 (5)   Tampa FL Regional



 
  Mississippi College 0 - 2 against Valdosta State

  Games:
    (L)  2017  Mississippi College 0  -  Valdosta State 6     South 1 Regional
    (L)  2017  Mississippi College 0  -  Valdosta State 8     South 1 Regional



 
  Mississippi College 1 - 0 against West Alabama

  Games:
    (W)  2024  Mississippi College 6  -  West Alabama 1     South 2 Regional



 
  Mississippi College 0 - 1 against West Florida

  Games:
    (L)  2025  Mississippi College 2  -  West Florida 3     South 2 Regional